NAD+ has been the hot anti-aging supplement for a minute, with everyone from Jennifer Aniston to Kendall Jenner to Joe Rogan hyping it up — but infusions are notoriously tough, lasting for hours and often coming with unpleasant side effects.
Now they’re about to get a whole lot easier.
Today, Remedy Place — the upscale wellness club with locations in Soho, Flatiron and West Hollywood — is selling injectable NAD+ Smart Pens that health-minded customers can use at home in just seconds.
What is NAD+?
NAD — short for nicotinamide adenine dinucleotide — is a coenzyme our bodies make naturally. It helps convert food into energy and repair damage, but we have less of it as we age.
Supplementation can give it a boost. Fans say it increases energy and metabolism, gives them more mental clarity, and reduces pain and inflammation. It can also be especially helpful for preparing for — or recovering from — long flights and time zone changes.
“You just feel fantastic. You feel really good,” Rogan said in a 2024 episode of his podcast.
Hailey Bieber went further in a 2022 episode of “The Kardashians,” raving, “I’m going to NAD for the rest of my life and I’m never going to age.”
But you shouldn’t actually mistake it for a fountain of youth.
“That sounds so gimmicky to me,” Remedy Place founder and CEO Jonathan Leary, DC, told The Post. “No, it’s about your cells being able to rejuvenate faster. As we get older, they can’t do that. And if you optimize these cells to be able to do that throughout the whole body, you can just start performing better.”
But infusions take hours — and take too much, too fast and people can feel nausea, stomach cramps, chest pressure or tightness, headaches, heat or lightheadedness.
How does the NAD+ pen work?
Enter their new injectable NAD+ Smart Pens, sold in partnership with NADclinic — an exclusive in the US. Each pen has 1000mg of pharmaceutical-grade NAD+ that you can keep in your fridge at home and inject on demand.
The smart pen, Leary says, is a “game changer” because it makes dosing flexible, allowing people to inject anywhere from 50mg 50 125mg at a time.
He recommends that new users start at the minimum dose — 50 mg, three times a week — and slowly increase to the typical 100mg dose.
“I think it’s always important, just like an ice bath or a sauna or a workout program or a nutrition program, like you want to titrate it based on how you feel, and then you can up accordingly,” he said.
What are the side effects like?
Because the pens deliver smaller doses on a consistent basis rather than big infusions farther apart, Leary says you’re less likely to feel all that discomfort — and in his experience, the benefits were greater, too.
“Since the R&D process of this, I’ve done more NAD than I ever have in my life — and I feel so much different,” he said.
“My skin looks so different, my sleep feels so different. I work 100 hours a week, and I’m on a plane two times a week. I’ve never had more demand on me mentally, physically or emotionally as an entrepreneur, but I feel so good.”
How much is it?
A single pen goes for $499, but prices go down if you buy multiple or pay for a subscription. They can be purchased at Remedy Place or shipped anywhere in the world within 48 hours.
They also all come with a Certificate of Analysis from an NHS/United Kingdom Accreditation Service-accredited laboratory.
Who should consider NAD+?
In a word — everyone. Leary says anyone who wants to “maximize their potential” can benefit, from young professionals to parents to middle-age adults who want to feel more youthful.
“A lot of science shows that we really start to see a shift [in NAD levels] after 30,” he explained. “This is for someone who’s like, I’m past the 30-year-old mark. I’m starting to feel a little bit different, and I don’t want to feel that.”
If the price of a pen feels like a once-in-a-while splurge as opposed to a regular addition to your wellness routine, Leary says to use it “whenever you’re under the most demand,” whether that be during a stressful time at work, while traveling, or when training for an athletic event like a marathon.
“Obviously the main focal point will always be the foundational pillars — movement, nutrition, mental health, human connection,” he said, but “things like NAD — these are the things that push you past that normal limit.”
