Should you be taking NMN or NAD+? That’s the latest question in the anti-aging debate.
If you’ve been swept into the longevity space, you’ve probably heard that NAD+ levels decline with age. With that drop could come a host of unwanted effects: accelerated aging, cognitive slowdown, muscle weakness and fatigue. That’s one reason NAD+ supplements have exploded in popularity in recent years.
But, experts and users warn that your NAD+ supplement might not be as effective as you think.
Several studies have shown that oral NAD+ gets broken down in the digestive tract, and its large polarity makes it more difficult to directly enter the cells. Some people turn to expensive NAD+ injections to bypass the issue, but there is another option: Nicotinamide mononucleotide (NMN).
NMN is a form of vitamin B3 that’s quickly absorbed in the gut and converted into NAD+ inside your cells.
Celebrities like Kim Kardashian and Bryan Johnson are already on NMN supplements, and if you know where to look, you can snag them yourself for around $60 on Amazon. One NMN formula in particular has quickly gained buzz, with reviewers saying they can actually feel the difference.
In a previous interview with The Post, Dr. Pooja Gidwani, a double board-certified internal and obesity medicine physician based in Los Angeles, explained, “NMN, as a precursor, is smaller, more bioavailable and readily converted inside cells into NAD+, making it a more effective oral approach.”
According to an article in the National Library of Medicine, NMN supplementation has shown some pretty impressive results in multiple studies, including reducing age-related fat inflammation, improving insulin secretion and supporting mitochondrial function.
NMN powders aren’t cheap — a single bottle usually retails for over $60 — but right now the Renue By Science NMN Powder is 15% off during Amazon’s Spring Sale. Users say it’s “worth it,” especially since one container lasts about 100 days.
The Renus by Science NMN Powder delivers about 500 mg of fast-absorbing NMN per serving, made from 100% pure crystalline Nicotinamide Mononucleotide. It’s third-party tested for purity and potency.
The powder is designed for sublingual (under-the-tongue) absorption, which the brand claims provides “superior bioavailability compared to standard capsules.” Users say the flavor is tolerable and the powder dissolves fast. And according to reviews, the results are noticeable quickly.
“I’ve used different NAD+ for a very long time… I’ve always liked NMN more, felt it was more effective,” one reviewer said, explaining why they switched over to NMN. “Didn’t take long to feel the difference. Not just general wellness and energy, but cognitively. I can tell I’m a little sharper.”
They’re not the only ones to notice the “difference”; hundreds of other reviewers report benefits ranging from sharper focus and better-looking skin to lower blood pressure. And that’s just after short-term use.
This article was written by Miska Salemann, New York Post Commerce Writer/Reporter. As a health-forward member of Gen Z, Miska seeks out experts to weigh in on the benefits, safety and designs of both trending and tried-and-true fitness equipment, workout clothing, dietary supplements and more. Taking matters into her own hands, Miska intrepidly tests wellness products, ranging from Bryan Johnson’s Blueprint Longevity Mix to the viral Oura Ring to Jennifer Aniston’s favorite workout platform – often with her adorable toddler by her side. Before joining The Post, Miska covered lifestyle and consumer topics for the U.S. Sun and The Cannon Beach Gazette.
